By Richard Hall of Ameriden® International, Inc.
Ramazanov’s Rhodiola Rosea
For centuries, the Alpine plant, Siberian Rhodiola rosea L., known as “Zolotoy koren or Golden Root” with its native habitat in the mountains of Eastern Siberia, has been giving new and longer life to thousands of Europeans. It is called “Golden Root” because the many generations before us have prized it above all other indigenous plants as “The Ultimate Traditional Medicine for General Health, Mental & Physical Performance and Longevity.”
The history, not myth or legend, of Siberian Rhodiola rosea’s extraordinary healing and invigorating properties extend back several thousand years, even to pre-written history of Siberia. For millennia, Siberian Rhodiola rosea was revered as a “gift of the spirits” by the people of the local region. Traditionally, this marvelous plant was given to betrothed Siberian couples to ensure the birth of many healthy children.
Spanning generations, the prime harvesting locations, time of year and method of extraction of the choicest of roots had been a well kept family secret, as well as tightly controlled Governmental Russian secret.
Only recently has the Western World gained the knowledge of Siberian Rhodiola rosea’s true Adaptogenic, timeless health promoting properties. Now, with over 35 years of clinically proven European studies and whose safety & efficacy rein as a phyto-medicine (natural plant medicine), most other natural substances pale in comparison as an alternative to drugs.
Despite the efforts of the Pharmaceutical industry to keep natural substance information from us, it is our sincere hope that the entire civilized World will become well-informed and excited about Siberian Rhodiola rosea and its personal health possibilities.
The profit to be made from such a great substance leads many companies to produce inferior products that may be harmful or even fatal to you.
Could you use a safe substance with a wide array of health benefits especially related to mental and physical performance that have been clinically demonstrated exclusively using standardized Siberian Rhodiola rosea root extract?
If so read on.
Siberian Rhodiola rosea root extract/tincture has been shown to possess anti-fatigue, anti-stress, and anti-depressant properties. It also increases the bioelectrical activity of the brain which improves memory and brain energy.
Need Physical and Sexual Performance?
Siberian Rhodiola rosea reduces exhaustion and accelerates the recovery processes after training or workouts. It also stimulates muscle energy status; glycogen synthesis in muscles and liver; muscle protein synthesis and anabolic activity. Throughout the years it has shown to substantially improve erectile dysfunction and/or premature ejaculation in men and normalizes their prostatic fluid.
Want to Increase Fat Burning (Lipolytic) activity?
Siberian Rhodiola rosea extract activates the lipolytic processes (fat breakdown) and mobilizes lipids from adipose tissue to the natural fat burning system of your body for weight reduction.
Could You Use Cardiovascular and Endocrine Health?
Siberian Rhodiola rosea extract has also shown clinically to reduce and/or prevent stress-induced cardiac damage, decrease myocardial catecholamines and cyclic adenosine monophosphate (cAMP) levels. It also reduces adrenal catecholamine release, activates µu-opiate receptors in heart muscle, preventing reperfusion arrhythmias. Siberian Rhodiola rosea extract clinically enhances thyroid function without causing hyperthyroidism, enhances thymus gland function and protects or delays involution that occurs with aging (Anti-aging). It also improves your adrenal gland reserves without causing hypertrophy.
How much should a person use?
Based on decades of research and consumer use, the following suggestions are recommended for American consumers interested in Siberian Rhodiola rosea extract products:
A.) Be sure the product contains true Siberian Rhodiola rosea root extract:
All informed consumers who expect to get the health benefits described within or demonstrated by available research on Siberian Rhodiola rosea extract should be certain that the product they are using actually contains true Siberian Rhodiola rosea extract. Siberia Rhodiola rosea should be clearly stated in the ingredient listing in the Supplement Facts box on the products label. In addition, you should also be certain that the Siberia Rhodiola rosea root extract listed is standardized to minimum 3% rosavins in the product supplement area.
B.) Siberian Rhodiola rosea extract should be sold either as a stand-alone, single ingredient product or as a synergistic ingredient in a formula with other compatible ingredients.
Formulated multi-ingredient combination extracted products may or may not be safe and effective, but in any case, it is not possible to generalize about the potential interactions of the different ingredients, which is beyond the scope of this review. Therefore, we would recommend that you take only single ingredient capsules or tablets containing standardized true Siberian Rhodiola rosea extract and/or in combination with synergistic ingredients known to enhance or be effective with standardized Siberian Rhodiola. rosea extract.
C.) More is not better.
Keep taking the optimal dose: Dosages differ from individual to individual. The recommended dose range of a 3% product (150><500 mg per day), studied and prescribed by hundreds of doctors, is the optimal or best amount that can generally be use as safe, effective relief from chronic stress effects. Much higher doses are not unsafe or toxic, but based on available research they are:
- Not likely to increase its effectiveness
- More likely to cause uneasiness or irritability especially when used in combination with prescribed drugs
That is why it is always best to consult with your Healthcare practitioner before taking any drug or drug-like substance.
D.) Reduce Your Stress- Include Siberian Rhodiola rosea extract as part of your stress management program
For best results, include taking Siberian Rhodiola rosea extract as part of your larger program picture for rebalancing and improving the health and well-being of your entire lifestyle. This comprehensive lifestyle program should include a healthy diet, regular exercise, the relinquishing smoking or substance abuse, moderation of alcohol, consistent weight management, making time for family and friends, improving communication and relationship skills, cultivating other interest outside of work (such as hobbies, travel, arts, education), and developing a sense of helping others.
E.) Consult Your Healthcare Professional:
Once again, anyone considering taking a dietary supplement containing standardized Siberian Rhodiola rosea root extract that has a serious medical condition or disability and/or is taking prescription medicine should consult their chosen healthcare practitioner before taking this or any other product.
Phytochemistry of Rhodiola Rosea
There are about 20 plant species of the genus Rhodiola. According to clinical studies, Siberian Rhodiola rosea root extract is the most biologically active. This is the reason this species has been well researched in Europe.
Health benefits related to mental and physical performance have been clinically demonstrated exclusively using only standardized Siberian Rhodiola rosea root extract.
When extracts of other Rhodiola species were substituted, these clinical benefits diminished or disappeared altogether.
Of equal importance, the toxicology on Siberian Rhodiola rosea root extract is also the most complete and its safety has been thoroughly investigated and confirmed. The Standardization of Siberian Rhodiola rosea extracts have now been cleared for prolonged human use. All history has proven that true Siberian Rhodiola rosea extract does not present any harmful adverse side-effects or undesirable interactions with conventional drugs when directed by healthcare practitioners, only excellent results for most people using it on a daily basis.
Why and How Siberian Rhodiola Rosea Root Extract Is Clinically Standardized & Tested
The standardization of Siberian Rhodiola rosea root extract is very important because it will help to prevent its adulteration/substitution with other ineffective species of the genus Rhodiola, which is usually very cheap and quite possibly not safe for human consumption.
In order that a person enjoy consistent and repeatable health promoting properties of Siberian Rhodiola rosea you must consume the clinically tested Siberian Rhodiola rosea root extract standardized to minimum 3% rosavins. The chemical composition of Siberian Rhodiola rosea root is different from the other plant species of the genus Rhodiola. Only Siberian Rhodiola rosea contains the Cinnamyl alcohol glycosides: rosavin, rosin and rosarin (the rosavins), monoterpenes rosiridin and salidroside, while other species of Rhodiola contain only salidroside.
True Siberian Rhodiola rosea root extract must contain rosavins, rosiridin and salidroside in ratios approximately 3:1:1 that reflect the phytochemistry of the natural plant. For example, the extract of Siberian Rhodiola rosea root should contain minimum 3% rosavins, 1% rosiridins and 1% salidroside.
In fact, products containing high salidroside or vaguely labeled Rhodiola in general terms without full botanical name, probably means that it is not made from true Siberian Rhodiola rosea root, and therefore lacks its clinically demonstrated health benefits as listed earlier on.
These unproven substitutes cannot be equivalent to Siberian Rhodiola rosea root extract and cannot claim equal safety and efficacy until they are independently proven by equivalent animal studies and clinical trials. To date the only Rhodiola product that has been clinically tested and proven safe for humans is true Siberian Rhodiola rosea extract standardized to a minimum of 3 percent rosavins.
“Beware of Substitutes”
Of the great benefits that can be derived from true Siberian Rhodiola rosea root extract, caution exists, only the extract from true Siberian Rhodiola rosea has been clinically studied which should make you the benefits you would expect from what you have read to this point. This definitely is part of the problem with popularizing a relatively new phytomedicine, such as standardized Siberian Rhodiola rosea root extract. Confusion arises when consumers are offered a variety of “Rhodiola” products; some much cheaper than others, without being given enough reliable information to judge for themselves which is the true Siberian Rhodiola rosea product. Many of these products are using other plant species of the genus Rhodiola or non-standardized extracts and hope to “ride on the coattails” of the marketing efforts of companies based on the research of true Siberian Rhodiola rosea. Once again, other species of Rhodiola are not equivalent to true Siberian Rhodiola rosea and there are little scientific or medical evidences that can be produced to show the same physiological effects and health benefits as do Siberian Rhodiola rosea extract. Some of these other products use misleading promotional materials or are even mislabeled to imply false equivalency with standardized true Siberian Rhodiola rosea extracts.
Unfortunately, the checkered history of the dietary supplement market, especially in the herbal category, has not yet reached its reassuring information about clear and effective consumer education. In fact, it offers far too many examples of the opposite. Good products often receive an unfair, undeserved and damaged public image from media sensationalism, misinformation and wealthy competitive confusion.
Ameriden International, Inc. has endeavored to achieve the public’s greatest approval in safety and assurance through testing and providing effective natural alternatives. Ameriden International, Inc. is one of only three alternative companies to be approved for participating in the Prestigious International (APA)American Psychiatric Association meetings held in various cities once a year around the world.
Ameriden’s Rhodiola rosea & Adaptogen products, for example, Rosavin™, Rosavin Plus® and ClearMind® have been spoken of in many Complementary Alternative Medicine (CAM) articles & books, including the following:
The Passing of Dr. Zakir Ramazanov
Dr. Zakir Ramazanov, president and owner of National Bioscience Corp., died suddenly last November 30th, 2006.
Dr. Ramazanov was well-known and respected worldwide, especially for his natural product research and development accomplishments.
Dr. Ramazanov applied innovative technology to the extraction of lycopene, beta-carotene and lutein from tomatoes and algae; the extraction and standardization of antioxidants from fruits and vegetables; the intensive biotechnological cultivation of Spirulina and marine plants in Africa; and the extraction of health promoting marine natural products. He introduced Siberian Rhodiola rosea to the North American marketplace in 1998, supporting this valuable dietary supplement with his characteristically strong scientific documentation and publications. He is and will continue to be greatly missed by all his friends.
Dr. Zakir Ramazanov was born in the former Soviet Union. In 1978, he received his undergraduate degree from Caucasian State University with a double major in biochemistry and plant physiology. He graduated at the top of his class with a special golden diploma. Later that year, he enlisted in the Soviet Army and served a tour of duty in Afghanistan. He first learned of Rhodiola rosea from a fellow soldier, whose mother sent him packets of the powdered herb to improve stamina.
Upon his return to civilian life, Dr. Zakir Ramazanov served as Head Engineer at the Institute of Solar Energy of the Soviet Union. There, he designed and constructed:
- Solar batteries and solar energy stations for potential use on orbiting space stations and in deserts.
- Solar bioreactors for the cultivation of dunaliella, chlorella, spirulina, and other algae
Dr. Ramazanov became Senior Scientist and Chief of the Department of Biotechnology of the Soviet Academy of Sciences. He was also Deputy Chairman of Biotechnological Programs for the Development of Aquatic Biotechnology for Medicine and Food in East European and Asian Countries. During this period, he developed new methods of cultivating algae for human consumption.
Dr Ramazanov left the Soviet Union in 1989, and worked with Professor Goran Samuelsson at the University of Umea in Sweden. He researched the intracellular mechanisms of carbon dioxide assimilation by aquatic plants and the biochemistry of cell adaptation to low and high carbon dioxide stress. In 1990, Dr. Ramazanov became Research Professor of Plant Biochemistry at the Universidad de Cordoba in Spain. In 1991, Dr. Ramazanov worked as a research fellow with Professor James Moroney at Louisiana State University Baton Rouge.
In late 1991, Dr. Ramazanov joined the Canary Islands-based Institute of Technology and Marine Sciences, becoming the Institute’s Director of Science. During the next four years, he developed eight plant-based dietary ingredients and authored two books.
Dr. Ramazanov received grants from:
- The Swedish National Science Foundation, the Swedish Institute of Natural Science, and the Swedish Royal Academy of Science, Umea University (1989)
- Ministerio de Educacion y Ciencia, Universidad de Cordoba (1990)
- SAREC, Sweden (scientific collaboration between Swedish and African Countries), University of Dar Es-Salaam, Marine Science Institute of Zanzibar, Republic of Tanzania (1991)
- Universidad de Autonoma de Madrid, Spain (1993)
- Universidad Las Palmas de Gran Canaria, Spain (1993)
- United States USAID for Development of Biotechnology Project in Central Africa (1993)
- National Science Foundation (USA), Louisiana State University (1994)
Summary of Dr. Ramazanov’s Academic and Scientific Achivements
- Is the inventor of five science and technology patents
- Has presented more than 40 papers to science meetings
- Has published over 140 articles
- Has authored several popular books on natural products and was an essential contributor to the recent publication of: The Rhodiola Revolution: Transform Your Health with the Herbal Breakthrough of the 21st Century (Hardcover) by Richard P. Brown, Patricia L. Gerbarg, Barbara Graham
Dr. Ramazanov is survived by his wife Svetlana, their son Arthur and their daughter Larissa.